Lung cells infection by Pseudomonas aeruginosa

Description:

Description: English: We were amazed to discover that the pathogenic bacteria Pseudomonas aeruginosa activates its virulence program within only 20 seconds after host contact! Pseudomonas aeruginosa grows by division, and intriguingly the two daughter cells behave differently. This asymmetric division produces two specialized cell types: a spreader for dissemination and a striker for local tissue damage. This is a step forward to understand how bacteria make decisions. This image illustrates Pseudomonas colonization of the host lung tissue. Technical description: Early infection of epithelial lung cells (blue, CellTrace CFSE) by the bacterial pathogen Pseudomonas aeruginosa (yellow, mCherry) (Mean of Infection: 40, 2 hours post infection, Image post treatment: the image is a Z-stack 2D projection, rendered with Adobe Photoshop CC using the Glowing Edges filter). Date: 30 January 2019. Source: Own work. Author: Benoit-Joseph Laventie.